US Employs Precision Strike Missiles in Ongoing Conflict with Iran

The United States has made a notable move by deploying Precision Strike Missiles (PrSMs) in its military operations against Iran. This marks a historic first in the ongoing conflict, with CENTCOM reporting extensive strikes targeting Iranian military capabilities. As tensions escalate, President Trump demands Iran's unconditional surrender, while Iran retaliates with strikes against Israel and Gulf nations. The situation remains fluid, with significant developments expected in the coming days.

By Narendra Chaudhary Mar 7, 2026, 08:35 IST

Introduction to the Conflict

In a significant development, the United States has utilized Precision Strike Missiles (PrSMs) for the first time in its ongoing military operations against Iran, as reported by US Central Command. The exact launch locations and specific targets of these missiles remain undisclosed. The US, alongside Israel, has conducted extensive strikes aimed at crippling Iran's military capabilities, leadership, and nuclear initiatives. The objectives and timelines of the conflict have frequently evolved, with the US occasionally indicating intentions to destabilize Iran's government or support new leadership from within.

Iran's Response and CENTCOM's Announcement

In retaliation, Iran has intensified its strikes against Israel and Gulf nations. CENTCOM announced, "In a historic first, long-range Precision Strike Missiles (PrSMs) were used in combat during Operation Epic Fury." CENTCOM Commander Brad Cooper expressed pride in the military's innovative approach to creating challenges for adversaries. A video released shows a PrSM being launched from a M142 High Mobility Artillery Rocket System (HIMARS) in a desert environment.

PrSMs, developed by Lockheed Martin, are long-range precision missiles capable of striking targets from distances of 60 km (37 miles) to over 499 km (310 miles). The first units were delivered to the US Army in December 2023. These missiles are compatible with both the MLRS M270 and HIMARS systems, which are also utilized by the UK and US armed forces.

CENTCOM's Target List and Military Actions

Overview of Targets and Military Assets

CENTCOM has disclosed a list of military assets and targets engaged during the initial week of the conflict. Reports indicate that US forces struck over 3,000 targets within the first seven days. The operations primarily focused on facilities associated with Iran's military leadership and defense systems, resulting in damage to several Iranian naval vessels. It is estimated that at least 43 Iranian ships were either damaged or destroyed during this period.

Many of the strikes targeted installations linked to the Islamic Revolutionary Guard Corps, a key component of Iran's military structure.

Trump's Stance on Iran

Demand for Unconditional Surrender

President Donald Trump stated that the US would not pursue negotiations with Iran unless the country agrees to "unconditional surrender." This announcement came as Washington prepared for a significant bombing campaign, anticipated to be the most intense phase of the week-long conflict. Concurrently, Israel initiated a series of strikes on Tehran, with reports and footage capturing explosions and smoke rising over the western areas of the capital.